Prediction of transcriptor factor binding site within the promoter region of one interesting gene. An approach practised by experimental biologists

by Alexey Kutsenko (MTC, Karolinska Institutet), Lorand Levente (MTC, Karolinska Institutet)

Wednesday 26 Sept 2007, 13:15 → 14:00 Europe/Stockholm

RB35

Expression of the Epstein-Barr virus (EBV) latent membrane protein (LMP1) is regulated by virus- and host cell-specific factors and plays an important role in switching between different types of EBV. The current thinking is that LMP1 is involved in host networks and the expression of LMP1 is controlled by host cell transcription factors (TF). Here we present the results of in silico prediction TF binding sites within the LMP1 promoter region in EBV sequence.