Nordita Events [before January 2018]
Sequence evolution in phenotypic space: An overview
by ,
→
Europe/Stockholm
Nordita seminar room
Nordita seminar room
Description
While most of the genetic information is coded in the DNA
sequence, the selection process acts on phenotypic traits.
It may well be the case that, while mutations affect
independently these traits, the selective effect (fitness)
is a nonlinear function of the traits themselves. I shall
recall a general approach to the description of this
two-layered evolution process, and I shall discuss recent
works in which evidence has been collected for it to take
place in
the evolutionary dynamics of transcription factor binding sites.