Protein microarrays for laboratory and on-site diagnosis - experimental methods and data analysis

by Jesper Gantelius (KTH)

Wednesday 18 Feb 2009, 16:00 → 17:00 Europe/Stockholm

RB35 (RB35)

Whereas DNA microarrays have for some time proven invaluable tools for biochemical analysis, for instance in the fields of SNP analysis, evolutionary genetics and mutation screening, protein microarrays have until recently lagged behind. Most protein microarrays are used for comprehensive mapping of protein-protein interactions. However, the use of protein microarrays for disease biomarker screening and diagnosis is also coming of age. In this talk, I will present several protein microarray platforms being employed and developed at KTH/Biotechnology that may find use in such health care areas as cancer, autoimmunity, allergy, and infection. Finally, I will briefly present the usual statistical framework employed by us for basic clustering and validation.