PhD programme halftime seminar: Protein function inference

by Mr Kristoffer Forslund (Stockholm Bioinformatics Centre)

Wednesday 8 Apr 2009, 16:00 → 17:00 Europe/Stockholm

RB35 (RB35)

This seminar will briefly summarize the work I have done so far within the PhD programme. The projects I have worked on to date have been directly or indirectly tied to improving and evaluating methods for inferring protein function, including interaction properties, by means of generally applicable, scaleable and potentially automated approaches. This includes work on the evolution of protein domain architectures, the link between protein domain architectures and protein function, and an evaluation of the relationship between functional conservation as found between orthologous proteins and evolutionary conservation of protein domain architectures. I will also report on an auxiliary project, recently submitted, which evaluates low-complexity filters in protein sequence similarity searches. Following this, I will discuss some leads I have for upcoming research.