Complex systems and Biological physics seminar [before December 2013]

Aligning graphs and finding substructures by message passing

by Hamed Mahmoudi (Helsinki University of Technology)

Europe/Stockholm
FB52

FB52

Description
In recent years, the theory of the networks has gained an important role in studying complex systems, ranging from molecular biology to social and technical networks. One interesting issue in this context is graph alignment problem where the goal is to find a matching of two graphs in a way that as many edges as possible are matched. Various known fundamental problems in combinatorial optimization such as the traveling salesman problem, the graph isomorphism and the maximum cliques, can be rewritten in terms of graph alignment. In this talk a message-passing algorithm will be introduced to study the graph-alignment and maximum-clique problem. As a proof of concept the algorithm is applied in a biology to detect to co evolution between interacting protein domain families in bacterial signal transduction.