How do cells detect, measure and respond to stresses?
by
Ala Trusina(The Niels Bohr Institute)
→
Europe/Stockholm
FA31
FA31
Description
The ever-changing harsh environment is one of the earliest challenges ancient organisms evolved to
deal with. To be able to survive these drastic changes in temperature, oxygen composition and other stresses — cells have evolved complex circuits of interacting proteins that can sense these changes and adjust the environment inside the cell to always maintain near-optimal conditions for cell functioning. I will talk about modeling approaches we use to analyze Unfolded Protein Response as well as more general feature of adaptation, present in several different stress response.