Ultrasensitive fluorescence spectroscopy and imaging - biomolecular studies and towards clinical diagnostics

by Jerker Widengren (KTH)

Tuesday 20 Apr 2010, 13:30 → 14:30 Europe/Stockholm

122:028

Ultrasensitive and ultrahigh resolution fluorescence spectroscopy and imaging techniques makes it possible to detect, identify and characterize biomolecules and biomolecular interactions down towards a single molecule level. This opens exciting perspectives in diagnostics, screening methodologies, and for fundamental dynamic and conformational studies of biomolecules. It is of major importance for the performance of these techniques to maximize the information extractable from the individual molecules studied. In this seminar, possible strategies to increase this information will be discussed. Moreover, an overview will be given, describing different activities in the group of Exp. Biomolecular Physics, where these fluorescence methods are applied, both for fundamental biomolecular studies, and with the aim to improve early stage cancer diagnostics.