Nordita seminar

Solitons and the genetic switch mechanism

by Antti Niemi (Nordita)

Europe/Stockholm
122:028

122:028

Description
The transition between the lysogenic and the lytic state in lambda phage infected E. coli bacteria is among the most extensively studied genetic switch mechanisms. The interplay between the lysogeny maintaining CI repressor protein and the CRO regulator protein that controls the transition to the lytic state is a simple model for more complex regulatory networks, including those that can lead to cancer. In this talk we describe the transition as a process, and propose that it could be understood in terms of a soliton-antisoliton pair annihilation.