Stockholm Bioinformatics Center seminars

Structure & function of metabolic networks

by Dr Petter Holme (Coputational Biology)

Europe/Stockholm
RB35

RB35

Description
Modern technology provide us with large amounts of biological data. This opens possibilities to study the large-scale organization and function of a biological system. The information is, however, typically not comprehensive enough to use the same tools for studying large-scale systems (e.g. the metabolism) as small subsystems (e.g. the citric acid cycle). I will discuss network theory in general, and how statistical graph theory can be used to study the organization of metabolism. Specifically I will talk about the role, definition and detection of "currency metabolites" -- ubiquitous substances (like water, carbon dioxide, ATP, etc.) that occur in a multitude of reactions.