: Shedding light on tumor metabolism: novel instruments to probe oxygen supply and demand.

by Dr Sarah Bohndiek (Department of Physics and Cancer Research UK Cambridge Institute, University of Cambridge, UK.)

Friday 30 Sept 2016, 15:15 → 16:00 Europe/Stockholm

FA32

Oxidative stress and metabolic alterations derived from inflammation and tumor growth lead to hypoxia and angiogenesis in cancer and are associated with disease aggressiveness as well as the evolution of drug resistance. There are few validated, non-invasive, methods to detect the spatiotemporal distribution of these processes. To overcome this limitation, we aim to create and apply novel imaging methods to study oxygen delivery and utilization in preclinical models and in patients. In this talk, I will given an overview of how biomedical optics can aid this research effort and focus on two emerging approaches: optoacoustic and hyperspectral imaging, detailing both their technological development as well as giving examples of their biomedical application in living subjects. Coffee and sandwiches will be served from 15:00 in room FA32.