The exploration-exploitation paradigm for the C.elegans brain growth
by
MrVito Dichio(Sorbonne University)
→
Europe/Stockholm
Zoom
Zoom
https://kth-se.zoom.us/j/68511745670
Description
The stochastic exploration of the configuration space and the exploitation of optimal (functional) states underlie many biological processes. The evolutionary dynamics stands out as a remarkable example. Here, we introduce a novel formalism that mimics evolution and encodes a general exploration-exploitation dynamics for biological networks. We then apply it to the brain wiring problem - i.e., the growth of the network of neurons and neuronal connections of a natural nervous system - focusing on the development of the C.elegans brain. We demonstrate that a parsimonious maxent description of the adult brain combined with our framework is able to track down the entire developmental trajectory.