The Universe is filled with non-baryonic Dark Matter which prevails the
known form of matter (leptons and baryons). Indirect Dark Matter search methods are sensitive to self-annihilating Dark Matter candidates: among the spray of particles released in the self-annihilation process,gamma-rays and to some extent neutrinos can be used to trace regions with high overdensities of Dark Matter. The energy of these photons reaches up to the mass of the annihilating particles. For Dark Matter particles moremassive than $100 \, \text{GeV}$, atmospheric Cherenkov telescopes become sensitive to these radiation energies while for less massive particles,
space-based detection techniques are favorable (e.g. with the recently
commissioned Fermi mission). Here, we present a summary of results
obtained with the H.E.S.S. experiment located in Namibia using four $100\, \text{m}^2$ optical telescopes to detect and image air Cherenkov lightfrom extensive air showers. The experiment has been used to search for annihilation radiation from various candidate regions with enhanced Dark Matter density.