by
Kevin J. Webb(Theoretical Chemistry/School of Biotechnology, KTH and School of Electrical and Computer Engineering, Purdue University, Indiana)
→
Europe/Stockholm
Oskar Klein Auditorium
Oskar Klein Auditorium
Description
Imaging of scattering media such as tissue using light provides the
potential to achieve safe and inexpensive instruments and allows for the
use of spectroscopy. I describe some fundamental aspects
of optical imaging in scattering media and discuss the information
that can be obtained by recording elastically scattered light.
I describe two complementary approaches, one based on the coherence
properties of light, where speckle occurs, and the other which neglects
coherence at optical frequencies and employs diffusion modeling, which
forms the basis of optical diffusion tomography. Imaging through many
centimeters of tissue is then possible. Optical contrast can
be enhanced through fluorescence, and, with targeting, high
sensitivity is possible. A clinical instrument would be driven
by a disease detection or health monitoring capability not provided by
other modalities.
