One of the most exciting observables in the cosmic microwave background (CMB) radiation, which could deeply impact our picture of the early universe, is non-Gaussianity. Within the inflationary paradigm, the detection of non-Gaussianity would gives us precious indications about the interaction of the inflaton, the main dynamical field in the early universe. The CMB perturbations can be non-Gaussian in a potentially infinite number of ways. Due to the complexity of the numerical analysis only a handful of non-Gaussian signals has been looked for in the data. I will describe a model of inflation in which a resonant mechanism can potentially generate a strong non-Gaussian signal. This resonant non-Gaussianity is completely different from the signals that have been so far considered and in fact it has less than 15% correlation with any other known non-Gaussianity. I will show that there are theoretically well motivated models of inflation that lead to resonant non-Gaussianity. I will present a concrete realization in string theory based on axion monodromy.