I will describe recent efforts to understand the mediation of supersymmetry breaking in compactifications of string theory whose moduli are stabilized by non-perturbative effects. I will review how geometric separation between the visible and the supersymmetry breaking sectors has been argued to lead to sequestering, and I will describe how moduli stabilization effects may spoil sequestering. In some of the phenomenologically most successful models, the effects of moduli stabilization can be significant and may induce non-negligible CP-violation and flavor changing neutral currents as well as problems for electro-weak symmetry breaking.
