Coarse-grained Simulation Studies of Mesoscopic Membrane Phenomena
by
Markus Deserno(Carnegie Mellon University)
→
Europe/Stockholm
Oskar Klein Auditorium (FR4)
Oskar Klein Auditorium (FR4)
Description
Lipid membranes exhibit a large spectrum of fascinating physical
behavior, spanning many orders of magnitude both in length- and time
scales. To cover this wide range, models of different resolution have
been developed. In the intermediate regime of about 100 nanometer length
scale and micro- to millisecond time scale mesoscopic coarse-grained
models have recently covered much ground. I will describe a particular
solvent-free coarse-grained model developed by us and illustrate its
applicability to a wide variety of phenomena, among them pore-formation
by amphipathic peptides, protein aggregation on critically mixed
bilayers, and membrane vesiculation driven by curvature-imprinting proteins.
