Complex Systems and Biological Physics Seminars

Spatial information dynamics in biological systems

by Jan Hoh (Johns Hopkins and KTH)

Europe/Stockholm
Description
Information is a fundamental notion in biology. However, more than 50 years after the prevailing mathematical framework for information was developed by Claude Shannon, quantitative consideration of information in biological systems is still rare in relationship to the extremely large body of relevant research. I will present details of a new metric for spatial information, the k-space information (kSI), where correlations between elements in a data are accounted for. Applications to several biological problems, including embryonic development and bacterial chemotaxis, will be presented. Findings to date suggest that the kSI may provide a powerful new tool for quantifying information in a wide range of biological systems, and with the potential to offer important new biological insights.