Speaker
Michael A Lomholt
(University of Southern Denmark)
Description
When a piece of circular DNA breaks in a nanochannel it
slowly unfolds to a linear conformation. I present a simple
model for the process, where the unfolding is driven by an
entropic force and opposed by hydrodynamic friction with the
channel walls. The model is compared with experimental data
using Bayesian inference. It is demonstrated that this
provides a conceptually simple way of extracting numerical
values for the force and friction from the experimental data.
