Speaker
Tetsuya Kobayashi
(University of Tokio, Institute of Industrial Science)
Description
Fitness, defined by the long-term growth of a population, is
the central quantity that characterizes the evolutionary
success of the population macroscopically. The innovations
of single-cell imaging and long-term tracking techniques
have revealed a huge heterogeneities in populations of
cells, and also enabled us to investigate how microscopic
behaviors of the single cells are linked to the macroscopic
properties of the population, including fitness. In
addition, it has been revealed that the problem of the
adaptation and evolution of growing populations shares a lot
with the information thermodynamics and the steady state
thermodynamics, suggesting that we can use the knowledge in
these fields for understanding the evolution. In this talk,
I attempt to outline how the problems of evolution and
thermodynamics are related. By highlight their similarities
and differences, I am going to show the open problems and
challenges in the evolution and adaptation at the cellular
level.