AlbaNova Colloquium

Cell Polarity and Diversity of Biological Shapes

by Kim Sneppen (Niels Bohr Institute)

Europe/Stockholm
Description

Despite continual renewal and damages of cells, an animal is able to maintain its complex morphology. How is this stability compatible with the complexity and diversity of living forms? Looking for answers at protein level may be misleading as diverging protein sequences anyway can result in similar morphologies. Inspired by the role of apical-basal and planar cell polarity in development, we propose that stability, complexity, and diversity are emergent properties in populations of polarized cells. When applied to specific developmental stages - gastrulation and the origins of folds and tubes – our model suggests that these are governed by an interplay between the two types of polar interactions.

https://stockholmuniversity.zoom.us/j/62663587311