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Ten years ago the IceCube Observatory at the South Pole discovered the diffuse flux of high-energy neutrinos that fills the cosmos. Since then, its origins have been coming into view, implicating sources with different properties at giga-parsec, mega-parsec, and kilo-parsec distance scales. I will discuss the most recent progress, with special attention to the evidence of neutrino emission from the nearby active galaxy NGC 1068, and to the results of searches for neutrinos from our own galaxy. I will also highlight the key role played by deep learning in these results.