Mikko Alava
(HUT, Espoo, Finland)
22/05/2013, 16:30
Opening of the workshop and practical information for the
Stockholm-Mariehamn trip.
Prof.
Chris Sander
(MSKCC)
22/05/2013, 16:45
Attributes of living systems are constrained in evolution.
An alternative to the analysis of conserved attributes
('characters') is analysis of functional interactions
('couplings') that cause conservation. A quantitative theory
of evolutionary couplings may be widely applicable to
biological and technical evolution at different scales of
phenomena. In a particularly interesting...
Prof.
Sui Huang
(Institute for Systems Biology)
22/05/2013, 18:00
The transition from one cell phenotype to another represents
a non-genetic (mutation-less) change of phenotype and plays
a central role not only in metazoan development
(differentiation) but also in cancer. From a systems
dynamics point of view such a (typically quasi-discrete)
“switch” of a cell in the stable steady state S(A) to state
S(B) can be formalized as a transition...
