Speaker
Mr
Lailai Zhu
(KTH Mechanics, Linne flow centre)
Description
We develop a code to resolve the fluid-structure interaction of
capsules in low-Reynolds-number flow, in 3D general geometries. We
use accelerated boundary integral method general geometry Ewald method
(GGEM), in the framework of the Navier-Stokes solver NEK5000 based on
spectral element method. A global spectral interpretation employing
spherical harmonics is incorporated simultaneously to resolve the
membrane dynamics. Two cases are investigated to illustrate the
generality of our implementation. We firstly show a capsule
transported in a 3D channel and/or duct with a 90 degree straight
and/or smooth curved corner, for a better understanding of moving soft
objects in geometrically asymmetric configurations. We examine the
effect of capsule elasticity and wall confinement in detail. Our
results give useful hints for the design of micro-devices. As a second
case, we simulate the capsule in flow past a cylindrical obstacle with
and without confinement, representing two popular cell separation
configurations, pinched flow fractionation (PFF) and deterministic
lateral displacement (DLL) respectively. In contrast to the original
methodology using fluid inertia, particle size or steric effect, we
numerically demonstrate the pure-elasticity-driven cell separation in
such devices.
Primary author
Mr
Lailai Zhu
(KTH Mechanics, Linne flow centre)
Co-author
Prof.
Luca Brandt
(KTH Mechanics, Linne flow centre)
