Speaker
Namiko Mitarai
(Niels Bohr Institute)
Description
Protein synthesis in bacteria is a very dynamical process.
Typically ribosomes start translation while the mRNA is
still being transcribed, resulting in
translation-transcription coupling. In addition mRNAs are
subject to active degradation. I discuss this complex
dynamics using a stochastic model of ribosome initiation and
traffic, especially focusing on recent experimental results
about interplay between ribosome dynamics and mRNA
degradation as well as transcription.