21 September 2015 to 16 October 2015
Nordita, Stockholm
Europe/Stockholm timezone

Dynamics of protein synthesis: transcription, translation, and mRNA degradation

22 Sept 2015, 11:00
1h
132:028 (Nordita, Stockholm)

132:028

Nordita, Stockholm

Speaker

Namiko Mitarai (Niels Bohr Institute)

Description

Protein synthesis in bacteria is a very dynamical process. Typically ribosomes start translation while the mRNA is still being transcribed, resulting in translation-transcription coupling. In addition mRNAs are subject to active degradation. I discuss this complex dynamics using a stochastic model of ribosome initiation and traffic, especially focusing on recent experimental results about interplay between ribosome dynamics and mRNA degradation as well as transcription.

Presentation materials

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