25–28 May 2011
Hotel Arkipelag, Mariehamn, Finland
Europe/Stockholm timezone

On Recycling and its Limits in Strand Displacement Systems

27 May 2011, 14:30
45m
Hotel Arkipelag, Mariehamn, Finland

Hotel Arkipelag, Mariehamn, Finland

Speaker

Prof. Anne Condon (University of British Columbia)

Description

We consider recycling, or reuse of molecules, in chemical reaction systems and their DNA strand displacement realizations. Recycling happens when a product of one reaction is a reactant in a later reaction. Recycling has the benefits of reducing consumption, or waste, of molecules and of avoiding fuel depletion. We will describe a binary counter that recycles molecules efficiently while incurring just a moderate slowdown compared to alternative counters that do not recycle strands. This counter is an n-bit binary reflecting gray code counter; it advances through 2^n states while consuming just O(n) molecules. In the strand displacement realization of this counter, the waste---total number of nucleotides of the DNA strands consumed---is O(n^3), while alternative counters have waste proportional to 2^n. We also show limits to the potential for recycling strands. In particular, our n-bit counter fails to work correctly when many copies of the species that represent the state (bits) of the counter are present initially.

Primary author

Prof. Anne Condon (University of British Columbia)

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