Control translations in bacteria

Mar 28, 2012, 1:30 PM
45m
132:028 (Nordita)

132:028

Nordita

Speaker

Dr Namiko Mitarai (Niels Bohr Institute, Copenhagen)

Description

Bacteria controls the levels of proteins via gene regulation. In this talk we focus on the regulation at the translation level, i.e., the process to convert information on mRNAs to proteins. We present three different ways of regulating translation, which are (i) small RNA regulation (ii) regulation of ribosome traffic jam (iii) toxin-antitoxin system. We construct mathematical models of each systems based on experimental knowledge to demonstrate the pros and cons of each regulations.

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