Statistical Mechanics of Biological Cooperativity

Session

Thursday afternoon

Thursday afternoon

23 May 2013, 16:00

Ferry Stockholm-Mariehamn and Hotel Arkipelag, Mariehamn, Åland

257. Acceleration of epidemic outbreaks by long-range dispersal

Prof. Oskar Hallatschek (MPI)

23/05/2013, 16:30

The spreading of evolutionary novelties across populations is the central element of adaptation. Unless population are well-mixed (like bacteria in a shaken test tube), the spreading dynamics not only depends on fitness differences but also on the dispersal behavior of the species. Spreading at a constant speed is generally predicted when dispersal is sufficiently short-ranged. However,...

258. Coupled Oscillators and Arnold Tongues in Cell Dynamics

Prof. Mogens Hogh Jensen (NBI)

23/05/2013, 17:15

Oscillating genetic patterns have been observed in networks related to the transcription factors NFkB, p53 and Hes1 [1]. We identify the central feed-back loops and found oscillations when time delays due to saturated degradation are present. By applying an external periodic signal, it is sometimes possible to lock the internal oscillation to the external signal. For the NF-kB systems in...

266. Using laboratory evolution experiments to study the genetic basis of cancer drug resistance in yeast

Prof. Ville Mustonen (Sanger Centre)

23/05/2013, 18:15

Understanding the molecular basis of the adaptive evolution of a population has relevance for important biological questions. For example, the problem of identifying genetic variants which underlie drug resistance, a question of importance for the treatment of pathogens, and of cancer, can be understood as a matter of inferring selection. A key problem in discovering variants under...