Prof.
Debora Marks
(Harvard)
24/05/2013, 09:00
Attributes of living systems are constrained in evolution.
An alternative to the analysis of conserved attributes
('characters') is analysis of functional interactions
('couplings') that cause conservation. A quantitative theory
of evolutionary couplings may be widely applicable to
biological and technical evolution at different scales of
phenomena. In a particularly interesting...
Prof.
Maurizio Serva
(University of Rio Grande do Norte - Brazil)
24/05/2013, 09:45
Compartmentalization of self-replicating molecules
(templates) in protocells is a necessary step towards the
evolution of modern cells. However, coexistence between
distinct template types inside a protocell can be achieved
only if there is a selective pressure favoring protocells
with a mixed template composition. Here we study
analytically a group selection model for the...
Prof.
Aleksandra Walczak
(ENS)
24/05/2013, 10:45
Recognition of pathogens relies on the diversity of immune
receptor proteins. Recent experiments that sequence the
entire immune cell repertoires provide a new opportunity for
quantitative insight into naturally occurring diversity and
how it is generated. The generation process is implemented
via a series of stochastic molecular events involving gene
choices and random nucleotide...
Prof.
Olivier Martin
(Universite Paris Sud - Orsay)
24/05/2013, 11:30
Even though many vital cellular process are known to be
tightly controlled, the associated regulatory network can
vary significantly from species to species. To explore the
space of all possible networks or circuits that implement a
specified control or function, we use Markov Chain Monte
Carlo (MCMC) and biophysical modeling. First, we show that
the molecular encoding of the genetic...