Speaker
Remi Monasson
Description
Olfactory receptor usage is highly heterogeneous, with some receptor
types being orders of magnitude more abundant than others.
Experimentally, increased exposure to odorants leads variously, but
reproducibly, to increased, decreased, or unchanged abundances of
different activated receptors. We demonstrate that this diversity of
effects can be understadood under the principle of efficient coding of
olfactory information when sensors are broadly correlated, and provide
an algorithm for predicting which olfactory receptors should increase or
decrease in abundance following specific environmental changes.
Finally, we give simple dynamical rules for neural birth and death
processes that might underlie this adaptation.
Primary author
Remi Monasson
