Speaker
Alessandro Mossa
Description
The manipulation of individual macromolecules made possible
by experimental techniques such as optical tweezers or
atomic force microscopy gives a unique insight into the
non-equilibrum thermodynamics of small systems. Besides a
general introduction about the theoretical and experimental
framework, this talk is focused on two topics: the proper
way of measuring the work applied to the system in a
single-molecule experiment, and a powerful generalization of
Crooks fluctuation theorem that allows the exploration of
misfolded and metastable states.
