Fluctuation Theorems and Single Molecule Experiments

Mar 18, 2010, 5:00 PM
Nordita Seminar Room 132:028 (Nordita)

Nordita Seminar Room 132:028



Alessandro Mossa


The manipulation of individual macromolecules made possible by experimental techniques such as optical tweezers or atomic force microscopy gives a unique insight into the non-equilibrum thermodynamics of small systems. Besides a general introduction about the theoretical and experimental framework, this talk is focused on two topics: the proper way of measuring the work applied to the system in a single-molecule experiment, and a powerful generalization of Crooks fluctuation theorem that allows the exploration of misfolded and metastable states.

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