Speaker
Prof.
Björn Högberg
(Karolinska Institute)
Description
CAD software for the design of 3D DNA origami nanostructures
have been reported previously. In caDNAno by Shawn Douglas,
and the more recent CanDo package by Castro and co-workers
the focus has been on designing structures where parallel
helices are packed in a square-, or honeycomb-lattice. In
our recent efforts in building a DNA nanopore, there has
been a need for a design software that allows a little bit
more freedom in the orientations of the double helices with
respect to each other. To this end we have implemented a
plug-in for the 3D modeling software Autodesk Maya. Here we
present this plug-in, called vHelix, and demonstrate how it
can be used to easily design previously untested DNA geometries.
Primary author
Prof.
Björn Högberg
(Karolinska Institute)