Prof.
William Shih
(Harvard Medical School)
26/05/2011, 09:15
I will present a general method for solving a key challenge
for nanotechnology: programmable self-assembly of complex,
three-dimensional nanostructures. Previously, scaffolded DNA
origami had been used to build arbitrary flat shapes 100 nm
in diameter and almost twice the mass of a ribosome. We have
succeeded in building custom three-dimensional structures
that can be conceived as stacks...
Prof.
Päivi Törmä
(Aalto University)
26/05/2011, 10:30
I present work where we propose a novel method for the
controlled positioning of carbon nanotubes on DNA
self-assembled structures. The method is based on the use of
streptavidin (STV)–biotin interaction. Precise assembly of
both a single CNT and CNT cross-junctions on DNA-origami
templates with relatively high yield is demonstrated. The
results thus make an essential contribution to the...
Prof.
Erez Dekel
(Weizmann Institute of Science)
26/05/2011, 11:15
Prof.
Björn Högberg
(Karolinska Institute)
26/05/2011, 14:30
CAD software for the design of 3D DNA origami nanostructures
have been reported previously. In caDNAno by Shawn Douglas,
and the more recent CanDo package by Castro and co-workers
the focus has been on designing structures where parallel
helices are packed in a square-, or honeycomb-lattice. In
our recent efforts in building a DNA nanopore, there has
been a need for a design software...
Dr
Lukas Bogunovic
(Universität Bielefeld)
26/05/2011, 15:15
We present our recent studies concerning micro-and
nanofluidic devices that are capable of detecting,
manipulating and separating single DNAs with different
lengths and conformations [1,2] and with complexed molecules
such as polymerases or chemotherapeutics [3,4].
The first device consists of a straight microchannel
structured with an array of non-conducting posts, which
create...
Dr
Josep Maria Huguet
(Universitat de Barcelona)
26/05/2011, 16:30
We have recently developed a methodology to infer the free
energy of hybridization of DNA with a single molecule
technique (Huguet et al., PNAS 107, 15431 (2010)). It
consists in unzipping a molecule of DNA of a few thousands
of base pairs with optical tweezers. These pulling
experiments provide a force vs. distance curve that is
analyzed to obtain the free energy of formation of...
Dr
Thomas Ouldridge
(Oxford University)
26/05/2011, 17:15
We have recently proposed a coarse-grained model of DNA [1]
which captures much of the thermodynamic and physical
changes associated with DNA duplex formation from isolated
single strands, in particular representing double-stranded
hybridization, hairpin formation and single-stranded
stacking consistently for the first time. Despite this, the
model is suciently simple to allow the study...
