Speaker
Kim Sneppen
(NBI)
Description
In the talk I will discuss how localized part of an eucaryotic
genome can be bistable. Bistable systems open for epigentics,
a central theme in regulation of living cells. It is
demonstrated that both copperativity and non-local
interactions along the DNA are needed to obtain bistability.
Further various localization mechanisms are discussed, with
aim of explaining how the system maintain boundaries between
silenced and active regions
along the chromosome.
