-
Prof. Debora Marks (Harvard)24/05/2013, 09:00Attributes of living systems are constrained in evolution. An alternative to the analysis of conserved attributes ('characters') is analysis of functional interactions ('couplings') that cause conservation. A quantitative theory of evolutionary couplings may be widely applicable to biological and technical evolution at different scales of phenomena. In a particularly interesting...Go to contribution page
-
Prof. Maurizio Serva (University of Rio Grande do Norte - Brazil)24/05/2013, 09:45Compartmentalization of self-replicating molecules (templates) in protocells is a necessary step towards the evolution of modern cells. However, coexistence between distinct template types inside a protocell can be achieved only if there is a selective pressure favoring protocells with a mixed template composition. Here we study analytically a group selection model for the...Go to contribution page
-
Prof. Aleksandra Walczak (ENS)24/05/2013, 10:45Recognition of pathogens relies on the diversity of immune receptor proteins. Recent experiments that sequence the entire immune cell repertoires provide a new opportunity for quantitative insight into naturally occurring diversity and how it is generated. The generation process is implemented via a series of stochastic molecular events involving gene choices and random nucleotide...Go to contribution page
-
Prof. Olivier Martin (Universite Paris Sud - Orsay)24/05/2013, 11:30Even though many vital cellular process are known to be tightly controlled, the associated regulatory network can vary significantly from species to species. To explore the space of all possible networks or circuits that implement a specified control or function, we use Markov Chain Monte Carlo (MCMC) and biophysical modeling. First, we show that the molecular encoding of the genetic...Go to contribution page
Choose timezone
Your profile timezone: